Archives: Articles

Reaching more cancer patients with CAR-T cell therapies

Reaching more cancer patients with CAR-T cell therapies

CAR-T cell therapeutics have emerged as one of the most revolutionary new treatments for aggressive cancers, with 6 commercial products already approved by the FDA to treat lymphomas and myelomas, and dozens more in development and clinical trial, including treatments for solid tumors. It’s a rapidly growing industry with a sizeable market of eligible patients […]

The Future of Lean Lab Implementations

The Future of Lean Lab Implementations

As laboratories become more and more digitalized and lab systems are increasingly efficiency-driven, many people may begin by asking whether Lean methodologies are still even relevant? In this blog, we hope to make a case for why they are, as well as to demonstrate how digitalization actually facilitates and enhances the implementation of lean labs. […]

Into the multiverse: predicting lab outcomes with BINOCS ‘what-if’ scenario analysis

Into the multiverse: predicting lab outcomes with BINOCS ‘what-if’ scenario analysis

In this third installment of our series investigating the role of project management techniques in BINOCS, we explore what-if scenario analysis (WISA) and how it can be used to help predict outcomes and mitigate risk in pharma capacity planning Many worlds lay before you Imagine that you are on an extended lunch break and decide […]

BINOCS Gantt: optimizing pre-clinical delivery for R&D labs

BINOCS Gantt: optimizing pre-clinical delivery for R&D labs

In this second article in our series on the role of project management methods in lab planning, we explore the challenges facing pre-clinical studies and how BINOCS can help R&D labs define and adhere to optimal development plans The road to regulatory approval In the previous blog in this series, we discussed the role of […]

Critical Chain Analysis: how project management concepts influence resource planning with BINOCS

Critical Chain Analysis: how project management concepts influence resource planning with BINOCS

Project management concepts are ubiquitous in modern planning, including in resource capacity planning systems. This extended blog explores the critical path and the critical chain concepts and their roles in resource management, including how they relate to the BINOCS system. If you already know a little bit about BINOCS, you know that we provide comprehensive […]

Zeroing-in on BINOCS in the Digital Lean Lab

Zeroing-in on BINOCS in the Digital Lean Lab

Let’s explore the role of BINOCS within the broader digital lean lab ecosystem. It is inspired by the “Digital Lean Lab” session organized by Ibec on 7 Oct 2021, featuring presentations by colleagues from Accenture, Astellas Pharma, and bluecrux. What is a “Digital Lean Lab”? The broad principles of the Lean Lab are rooted in […]

Analytical Method Validation: developing your mission control centre with BINOCS

Analytical Method Validation: developing your mission control centre with BINOCS

In Part 1 on our series of blogs on Analytical Method Validation, we discussed the ways in which it shares key features with space missions; in Part 2 we’ll explore how you could set up your lab’s very own “mission control center” using the BINOCS resource management system  What is Analytical Method Validation?  QC laboratories do far more than perform release and stability testing. In fact, while such business-critical […]

Hitching a horse to your Ferrari: BINOCS and the risks of retaining legacy systems

Hitching a horse to your Ferrari: BINOCS and the risks of retaining legacy systems

Planning and scheduling without a co-bot management system is hard. Before choosing to implement BINOCS, many labs spend months or even years investing in methods to make their manual processes more manageable. Here we use some common examples to illustrate how importing a legacy system is often redundant when you’ve already upgraded to a more […]

Analytical Method Validation: it’s not brain surgery (but it might be rocket science)

Analytical Method Validation: it’s not brain surgery (but it might be rocket science)

Since both Richard Branson and Jeff Bezos have recently entered orbit, we explore what commercial space flights can tell us about QC process validation  Major Gagarin to Ground Control  Across the centuries, dreamers everywhere have sought to reach for the heavens. In practice, there are many obstacles to humanity touching the stars, the biggest and most significant hurdle being the act of escaping the Earth’s gravity – to paraphrase Newton, “what […]

Lab Automation: how to make your business case?

Lab Automation: how to make your business case?

In 2008, a survey on laboratory automation concluded that most lab workers (88%) believed they would rely on lab automation in the future. Yet it’s 2021, and 72% of scientists now say their sector is lagging behind. The lab of the future seems to have been put on hold. Society’s fascination with automation focuses on […]