BINOCS Articles

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Reaching more cancer patients with CAR-T cell therapies

CAR-T cell therapeutics have emerged as one of the most revolutionary new treatments for aggressive cancers, with 6 commercial products already approved by the FDA to treat lymphomas and myelomas, and dozens more in development...

The Future of Lean Lab Implementations

As laboratories become more and more digitalized and lab systems are increasingly efficiency-driven, many people may begin by asking whether Lean methodologies are still even relevant? In this blog, we hope to make a case...

Into the multiverse: predicting lab outcomes with BINOCS ‘what-if’ scenario analysis

In this third installment of our series investigating the role of project management techniques in BINOCS, we explore what-if scenario analysis (WISA) and how it can be used to help predict outcomes and mitigate risk...

BINOCS Gantt: optimizing pre-clinical delivery for R&D labs

In this second article in our series on the role of project management methods in lab planning, we explore the challenges facing pre-clinical studies and how BINOCS can help R&D labs define and adhere to...

Critical Chain Analysis: how project management concepts influence resource planning with BINOCS

Project management concepts are ubiquitous in modern planning, including in resource capacity planning systems. This extended blog explores the critical path and the critical chain concepts and their roles in resource management, including how they...

Zeroing-in on BINOCS in the Digital Lean Lab

Let’s explore the role of BINOCS within the broader digital lean lab ecosystem. It is inspired by the “Digital Lean Lab” session organized by Ibec on 7 Oct 2021, featuring presentations by colleagues from Accenture,...

Analytical Method Validation: developing your mission control centre with BINOCS

In Part 1 on our series of blogs on Analytical Method Validation, we discussed the ways in which it shares key features with space missions; in Part 2 we’ll explore how you could set up your lab’s very own “mission control center” using the BINOCS resource management system  What...

Hitching a horse to your Ferrari: BINOCS and the risks of retaining legacy systems

Planning and scheduling without a co-bot management system is hard. Before choosing to implement BINOCS, many labs spend months or even years investing in methods to make their manual processes more manageable. Here we use...

Analytical Method Validation: it’s not brain surgery (but it might be rocket science)

Since both Richard Branson and Jeff Bezos have recently entered orbit, we explore what commercial space flights can tell us about QC process validation  Major Gagarin to Ground Control  Across the centuries, dreamers everywhere have sought to reach for the heavens. In practice, there are many obstacles to humanity touching the...

Lab Automation: how to make your business case?

In 2008, a survey on laboratory automation concluded that most lab workers (88%) believed they would rely on lab automation in the future. Yet it's 2021, and 72% of scientists now say their sector is...

Resource Scheduling: How Much Lab Automation is Too Much?

So, you’ve automated 80% of your scheduling work, and now you want to take the next step towards making it to 100%. Not so fast! First, let’s take a closer look at lab automation and...

Challenges in scaling up the supply chain and manufacturing operations for CGT products.

Next-generation therapeutic products, including CAR-T and AAV-based, are already on the market and being used to treat previously untreatable conditions. These products are the future of healthcare, with more than 1,300 trials currently underway with...

The Hidden Costs of Using Excel for Resource Management.

Common issues when using Excel for resource management I’ve been using spreadsheet apps during my entire career (almost 30 years now). It started with Lotus Symphony on an IBM PC AT, then Lotus 123 and...

How to Choose The Right Laboratory Resource Planning Software?

Are you thinking about digitalizing your laboratory resource planning & scheduling? Maybe already listing a couple of potential software vendors? Eventually, you want to arrive at a cloud-based, laser-focused enterprise software that makes the end...

Planning Your QC Lab with APS Software: is it a Good Idea?

Advanced planning & scheduling tools like OMP, Quintiq, Ortems, Preactor, bioG… help manufacturers plan their production processes. APS software focuses on optimizing production fulfillment, safeguarding service levels, and managing inventory in the network. Often, we...

How to orchestrate cell & gene therapy supply chains, different in all its aspects

About a year and a half ago, we were asked by a client in the US to help them implement capacity planning & detailed scheduling for manufacturing and quality operations in a CAR-T cell &...

How to tackle manufacturing planning for Cell and Gene Therapy (CGT)?

Cell and gene therapies are here, and they’re here to stay. In the last couple of years, very promising results were achieved. Examples include treatments for certain blood cancers that helped patients for which all...

Freezing tasks in a project plan? Hmm…

The project managers shouts: “I want to freeze my activities. I had confirmed resources in my plan until last week, and now…. How can I plan my project in a proper way?”. It’s a completely...

Do you need a PMO or an RMO?

Christmas and New year pulled me away from the day-to-day rush and that was inspiring. The past three years, I focused on how organizations can improve resource utilization, especially for knowledge workers in environments such...

Not Every App is an Enterprise App.

The primary objective of the people who buy enterprise app is good, actionable output. App developers know this, and seduce buyers with the most fancy graphs, KPI dashboards and reports. Showing compelling output for a...